female mice due to insufficient numbers of surviving control mice. ©2018 WebMD, Inc. All rights reserved. Data sources include IBM Watson Micromedex (updated 2 Sep 2020), Cerner Multum™ (updated 1 Sep 2020), Wolters Kluwer™ (updated 31 Aug 2020) and others.
doses of 20 to 25 mg/kg. The effects of some drugs can change if you take other drugs or herbal products at the same time. Your doctor or pharmacist can often prevent or manage interactions by changing how you use your medications or by close monitoring. Talk to your pharmacist for more details.
doses of pyrazinamide in excess of 3 g twice weekly have been administered. Unnecessary use or misuse of any antibiotic can lead to its decreased effectiveness. Tell your doctor if you have any changes in weight. If you are taking this drug on a weekly schedule and miss a dose, take it as soon as you remember if it is on the same day. in Children and Adults, Pyrazinamide Tablets USP contain pyrazinamide 500 mg.
Other drugs may interact with pyrazinamide, including prescription and over-the-counter medicines, vitamins, and herbal products. Pyrazinamide is a prodrug that stops the growth of M. tuberculosis.
Pill Identifier Tool Quick, Easy, Pill Identification, Drug Interaction Tool Check Potential Drug Interactions, Pharmacy Locater Tool Including 24 Hour, Pharmacies, elliptical, white, imprinted with P 36, LL. There are few reliable in vitro tests for Pyrazinamide resistance.
Your pharmacist can provide more information about pyrazinamide. The net effect is that more pyrazinoic acid accumulates inside the bacillus at acid pH than at neutral pH. It is used with other drugs to treat tuberculosis. for an elderly patient should be cautious, usually starting at the low end of
It is taken by mouth.
1990 ; 55 (212) (Nov 1):
Pyrazinamide is usually taken once per day. You may report side effects to FDA at 1-800-FDA-1088. 8. You will be prescribed pyrazinamide to … To help your doctor and pharmacist give you the best care, be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products) before starting treatment with this product. [4] It is not generally recommended for the treatment of latent tuberculosis. See additional information. Treatment of tuberculosis and tuberculosis infection in adults
their situation. drugs in vitro.
Store at room temperature away from moisture and heat. USES: Pyrazinamide is used with other medications to treat tuberculosis . You should not use pyrazinamide if you have active gout or severe liver disease.
Pyrazinamide has the following structural formula:C5H5N3O M.W. Other side effects include nausea and vomiting, anorexia, sideroblastic anemia, skin rash, urticaria, pruritus, dysuria, interstitial nephritis, malaise, rarely porphyria, and fever. Follow your doctor's instructions about any restrictions on food, beverages, or activity. Medical uses. Clinical monitoring and supportive therapy should be employed. It is not generally recommended for the treatment of latent tuberculosis.
For the best possible benefit, it is important to take each scheduled dose of this medication as directed. Pyrazinamide should always be administered with other effective antituberculous drugs. 617480012_PB. It has no other indicated medical uses.In particular, it is not used to treat other mycobacteria; Mycobacterium bovis and Mycobacterium leprae are innately … You may need to take pyrazinamide for only the first 2 months of your full course of treatment. Am Rev Respir Dis.
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